Bristol Myers Squibb Research Scientist in Redwood City, California

Research Scientist

Company

Bristol-Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases.

Position

The department of Immuno-Oncology Discovery at Bristol Myers Squibb, Redwood City is seeking a highly motivated Research Scientist to join a group of researchers evaluating novel therapies in the field of cancer immunotherapy. The candidate will characterize immuno-modulatory antibodies, and explore mechanism of action and combinatorial therapeutic strategies.

Qualifications

  • Master degree in immunology, oncology or related field and a minimum of 4 years of experience or BS with a minimum of 7 years of experience

  • Enthusiasm about immuno-oncology research

  • Knowledge of immunology including markers, functions, and interactions of immune cell subsets, immunotherapy modalities, antibodies

  • Proficiency in the following laboratory techniques is required:

  • Immune cell isolation from whole blood (one of the following: Ficoll and MACS, RosetteSep, EasySep, etc.)

  • Functional assays with primary immune cells (myeloid, B, or T cells)

  • Multi-color flow cytometry (8 or more channels, operate BD or BC flow cytometers)

  • ELISA or ELISPOT or Luminex

  • Mammalian cell culture

  • Tissue/tumor dissociation into single-cell suspension

  • Data analysis using GraphPad/Prism and SoftmaxPro

  • Proficiency in the following laboratory techniques is strongly preferred:

  • IP/WB (immunoprecipitation)

  • Phospho-flow

  • Proficiency in the following laboratory techniques is a plus:

  • Functional assays to measure phagocytosis or NK/CD8 cytotoxicity (flow- or imaging-based)

  • Assays to evaluate bispecific antibodies or CAR-T cells

  • Excellent interpersonal skills with the ability to work both independently and collaboratively in a dynamic and innovative research environment

  • Detail-oriented, with excellent organizational, and record-keeping skills

Bristol-Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.